WebMAGICKAL HOODOO VOODOO HEALING SUPERFOODS. Melanins produced by Exophiala pisciphila and Aspergillus bridgeri ICTF-201 exhibited a significant DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity comparable with that of synthetic melanin, indicating its antioxidant potential [102, 103]. Llaila O. Afrika. I have summarised and bulletpointed his main points. Microorganisms are also more feasible sources of pigments in comparison to pigments extracted from plants and animals because they do not have seasonal constraints, do not compete for limited farming land with actual foods, and can be produced easily in the cheap culture medium with high yields [16]. This result is related to melanin production during growth of the MEL1 mutant, since the biomass 48 hours is slightly pigmented, while the 72 hours biomass is dark due to the increased production of pigment [157]. For example, the pigment production by Penicillium sp. In a recent study, our group characterized the pigment produced by A. nidulans mutants as DOPA-melanin according to the results obtained with specific inhibitors of DHN- and DOPA-melanin pathways [93]. We also showed that the toxicity of A. nidulans melanin on mouse fibroblast McCoy cell line, after metabolic activation with hepatic S9 microsomal fraction, was much lesser (CI50 = 413.4 3.1 g/mL) than known cytotoxic agents such as cyclophosphamide (CI50 = 15 1.2 g/mL). Amazon.com: Melanin Research Foundation: Books 1 result RESULTS Melanin: Energy from Light and the Soul's Ascent by Melanin Research Foundation | May 3, 2015 20 Kindle $399$6.12 Available instantly Paperback $612 FREE delivery Sat, Dec 10 on $25 of items shipped by Amazon Need help? Studies have shown that melanin of zoopathogenic and phytopathogenic fungi is essential for their parasitizing, due to its antioxidant properties [101]. Access To Status Law Class #1.. What is Status?. 2 (2012): 202-11,https://doi.org/10.1016/j.taap.2012.08.002. Want to read. Scientists have identified three forms of melanin in humans: eumelanin. Studies have shown that the media composition and cultivation conditions affect the pigment production in fungi and the manipulation of these parameters can result in an increase in pigment yield for large-scale pigment production. Studies have demonstrated that the promoting or repressing effect of a nitrogen source on pigment production is strain dependent. Keywords fungi pigment melanin [13]. WebTHE GREAT BOOK OF MELANIN RESEARCH!!! Geoffrey Goodman and Dani Bercovich, Melanin Directly Converts Light for Vertebrate Metabolic Use: Heuristic Thoughts on Birds, Icarus and Dark Human Skin,Medical Hypotheses71, no. The Pineal gland is the first gland developed in your body, and appears in homo-sapiens a mere 3 weeks after conception. Sheng Meng and Efthimios Kaxiras. Large amounts of agro-industrial residues generated from diverse economic activities have attracted strong industry interest on the utilization of these residues as inexpensive substrates to support the growth of microorganisms in bioprocesses. WebThis volume goes over the brain hemispheres, history of religion, Black founders of civilization, the Sun, cosmology and cosmogony, the subjective and objective realms of being, analysis of cosmological system and view of man, spiritual anatomy of man, types of man and the cultivation of the spiritual man, the Tree of Life initiation system, It has been reported that fungal melanin arranged in nanoparticles protects against extremely high levels of ionizing radiation and suggests that the protective efficacy of this pigment is a function of its chemical structure, the presence of stable free radical, and spatial arrangement [18]. The presence of melanin in the cell wall is also correlated with enhanced virulence of parasitic fungi, as Paracoccidioides brasiliensis, Sporothrix schenckii, and Exophiala (Wangiella) dermatitidis [17, 20, 21]. Due to a planned power outage on Friday, 1/14, between 8am-1pm PST, some services may be impacted. It serves a wide range of additional physiological roles, including free radical scavenging, charge transfer, toxicant chelation, endocrine functions,16and gene protection. According to Dr Timothy Moore In humans, melanin is the primary determinant of skin and hair colour Experimental evidence shows that the accumulation of 90Sr by conidia or mycelium by a range of microfungal species is greater in pigmented than in unpigmented species [158]. The optimization of medium composition is an important strategy to increase pigment production because some sources of carbon and nitrogen can be more easily assimilated and promote higher yields of the desired product. The protective action of melanin is related to its high efficiency to absorb and scatter photons, particularly the higher-energy photons from the UV and blue part of the solar spectrum. According to the authors, these media contain nutrients that can regulate the expression of genes of interest and activate metabolic pathways important for the production of pigments. 25. A second group of mice was fed white, melanin-poor porcini mushrooms, a third group ate white porcini mushrooms that were supplemented with melanin, and a final control group received no mushrooms or melanin at all. An ideal pigment-producing microorganism should be capable of using a wide range of C and N sources; must be tolerant to pH, temperature, and minerals concentration; and must give reasonable pigments yield. But this evolutionary adjustment may have come at a significant cost. Studies have shown that synthetic melanin-like nanoparticles complexed with paramagnetic Fe3+ ions have potential as a highly efficient and nontoxic contrast agent for magnetic resonance imaging instead of Gd3+-based contrast agents, which can cause nephrotoxicity [136]. I) by Carol Barnes Melanin: The Organizing Molecule Berkley CA: Institute for the Study of Consciousnesses (Thesis) Message To The Blackman in America by Elijah Muhammad Metu Neter Vol. #THE-LUCIFERIAN-DOCTRINE%^ACHIEVE.!EVERYTHING.THAT.YOU.TRULY. web pages WebGREAT BOOK OF MELANIN RESEARCH PUBLIC OFFICIAL BONDS BOOK (POB) Public Official Bonds - Make Them Pay!!! These authors concluded that the cultivation in the total absence of light increased biomass and production of extracellular and intracellular pigments in all fungi. Search the history of over 797 billion The biosynthetic pathway of the dihydroxyphenylalanine (DOPA)-melanin in fungi. This book could save your life! $33.33. Owing to its semiconductor property, melanin becomes a promising material for organic bioelectronic devices like transistors, sensors, and batteries [121]. As a member, you receive exclusive content, community access, behind-the-scenes updates, and the pride of fueling work that matters to you. By making research easy to access, and puts the academic needs of the researchers before the business interests of publishers. This effect was observed for Cryptococcus neoformans, whose in vitro melanization has been associated with resistance against host effector cells, oxidants, microbicidal peptides, and amphotericin B [2325], and in Wangiella (Exophiala) dermatitidis, when the polyketide synthase gene WdPKS1 associated on melanin production was disrupted, this strain has become more susceptible to voriconazole and amphotericin B [26]. Melanin is a biological molecule associated with pigmentation in humans and animals. 24. Keywords fungi pigment melanin Potential also exists to use melanin films as an effective radiation sensitizer that could greatly improve the spectral range and efficiency of superconducting transition-edge bolometers [137]. It has been reported that the iron-melanin coating markedly enhances the catalytic activity of the gold nanoparticles (AuNPs) for both the hydrogen peroxide electroreduction and hydrogen evolution reaction [135]. First published October 15, 2009. The probable mechanism of action was suggested by a study published inBioelectrochemistry,30in which ionizing radiation was found to alter melanins oxidation-reduction potential. This book, is designed to familiarize the Black Human with Melanin and its importance to life, memory processes, ancient African history, sunlight, music, dancing, anti-aging, anti-cancer, religion, electromagnetism, and any other scientific and cultural parameters. 68 pages, Paperback. 2020 GreenMedInfo LLC. The mystery of melanins role in human physiology, and its potential to confer profound health protective and promoting properties, is explained in the excerpt below from Chapter 3 of Sayer Jis bookREGENERATE: Unlocking Your Bodys Radical Resilience Through The New Biology. The albatross, for instance, is capable of traveling 10,000 miles in a single flight, a bioenergetic feat that has long baffled the scientific community. Humans with lighter skin tones may have gained vitamin D accessibility at the expense of the ability to convert sunlight into metabolic energy. Vittorio Brena Back To Tokyo / Yesenia. In vitro studies have shown that melanized fungi are more resistant to UV light-induced and oxidant-mediated damages, temperature extremes, hydrolytic enzymes, heavy metal toxicity, and antimicrobial drugs than those nonmelanized [10, 1417]. Melanin pigment of Fonsecaea pedrosoi has antioxidant potential by reducing Fe(III) to Fe(II), ensuring the balance of its redox chemical microenvironment and minimizing the effect of oxidation of fundamental structures on fungal growth [104]. In Monascus ruber, it was observed that the highest levels of pigments production were obtained at an aeration rate of 0.05 L min1, which appeared to be clearly sufficient for providing the fungus with oxygen and removing carbon dioxide [57]. This will allow me to plunge deep into my bag of information acquired over the years as well as the knowledge gained from film school to create videos full time. WebMAGICKAL HOODOO VOODOO HEALING SUPERFOODS. [145] reported that thin films of melanin were found to enhance Schwann cell growth and neurite extension in rat pheochromocytoma cells (PC12 cells) compared to collagen films in vitro. To date our community has made over 100 million downloads. Not only can melanin convert light into heat, but new research raises the possibility that it can also transform other forms of radiation into metabolically useful forms of energy. Another study reported that melanized fungus Armillaria adsorb high concentrations of cations from the surrounding environment; some ions (Al, Zn, Fe, Cu, and Pb) were 50100 times more concentrated on rhizomorphs than in soil [156]. Melanin films also induced an inflammation response that was comparable to silicone implants in vivo, and the implants were significantly resorbed after 8 weeks. Home > Mechanisms for UltrafastNonradiative Relaxation in Electronically Excited Eumelanin Constituents,Biophysics Journal95, no. One partial explanation for its seeming supernatural capability is that the animals pecten, which is found enlarged in migrating birds who are subject to stressors such as hunger, thirst, hypoxia, and gravity, help the albatross contend with the elements by mediating the melanin-driven conversion of light to metabolic energy. It has been reported the use of melanin, a biopolymer with good biocompatibility and biodegradability, intrinsic photo-acoustic properties, binding ability to drugs, and chelating property to radioactive metal ions, as an efficient endogenous nanosystem for imaging-guided chemotherapy [152]. [3]. In particular, it can be considered a promising material for sensors and photovoltaic devices, due to broadband spectral absorbance and charge transport properties [128]. xanonymous According to the authors, melanin nanoparticles could successfully enter into the tumor and act as an efficient drug-delivery system, thereby greatly increasing the safe utility of the drugs for tumor treatment and significantly lowering the dosage used and its side effects. The study performed by [114] showed that the expression of inducible nitric oxide synthase gene decreased and lower levels of cytokines, such as IL-12 and TNF-, were observed when activated macrophages were incubated with melanized cells of the Fonsecaea monophora fungus. Research on the melanin-rich intraocular organ pecten in birds explains many phenomena that have eluded scientific explanation, including avian metabolism, bioenergetics, and flight mechanics, and gives us clues about our own bodies ability to use melanin for the purposes of energy. In Melanin, the Master Molecule, researchers summarize several decades worth of knowledge on melanin and its physicochemical properties. 1 (2015): 32-41,https://doi.org/10.2174/1871524915666150203093656. Bull [89] identified dopachrome (indole 5,6-quinone 2-carboxylic acid) and melanochrome (indole 5,6-quinone), which are intermediates in the DOPA-melanin pathway, in A. nidulans mutants defective in the production of melanin. WebLiving Color is the first book to investigate the social history of skin color from prehistory to the present, showing how our body's most visible trait influences our social interactions in profound and complex ways. Most Ascomycota fungi synthesize DHN-melanin from the polyketide synthase pathway, whereas few species are able to produce melanin through L-DOPA, in a pathway that resembles mammalian melanin biosynthesis [1113]. In literature, studies have confirmed that fungal melanin acts as metal chelators, enhancing the biomass-metal interaction and consequently its biosorption capacity [14]. A study conducted in our laboratory evaluated the use of corn steep liquor, sugarcane bagasse, and molasses as nutritional source on pigment production by melanin-overproducing mutant (MEL1) from A. nidulans. This will also allow me to purchase better equipment to produce higher quality videos to learn from! I have summarised and bulletpointed his main points. Another study in Monascus sp. In addition, these organisms can be genetically modified to increase productivity and quality of the produced pigments [37, 38]. (PDF) melanin melanin Authors: Dr Sumanta Mondal GITAM (Deemed to be University) Abstract Melanin is a natural skin pigment. [116] showed that Lachnum extracellular melanin (LEM404) had strong anti-ultraviolet radiation activity because the survival rates of Escherichia coli, Staphylococcus aureus, and Saccharomyces cerevisiae under UV radiation were significantly increased after in vitro addition of LEM404. Packed with knowledge of the food of the gods. Brief introduction to this section that descibes Open Access especially from an IntechOpen perspective, Want to get in touch? WebMelanin, the What, the Why and the How: An Introductory Review for Materials Scientists Interested in Flexible and Versatile Polymers A. Bernardus Mostert Citation:Mostert, A.B. The same enzyme, tyrosinase, carries out both steps. Edited by (PDF) melanin melanin Authors: Dr Sumanta Mondal GITAM (Deemed to be University) Abstract Melanin is a natural skin pigment. WebMelanin, the What, the Why and the How: An Introductory Review for Materials Scientists Interested in Flexible and Versatile Polymers A. Bernardus Mostert Citation:Mostert, A.B. Melanin is a biological molecule associated with pigmentation in humans and animals. J101 reported that the yield of pigment at 25C was ten times higher than at 30C, probably due to long growing (120 hours) and lower viscosity of the broth at 25C compared to 30C [49]. 30. Owing to their ability to increase the permeability of the blood-brain barrier, the melanin is also useful as carriers for other therapeutic agents, which must reach brain tissue to produce their therapeutic responses [144]. In the genus Aspergillus, DHN-melanin has not been identified in some members, as A. nidulans and A. niger. Cracks in 100% nearly all topic of importance to you, like. 6 (June 2008):890-99,https://doi.org/10.1016/j.jenvrad.2007.11.020. Hydroxylation (and decarboxylation) yields dihydroxyindoles, which can polymerize spontaneously to form DOPA-melanin [10, 27, 97]. Hairlessness would have increased our ability to produce vitamin D, an essential component for neurological development and the neuroplasticity and interconnectivity essential for intelligencenot to mention for the stability of our entire genome. $33.33. It was assumed that melanin pigments, participating in redox reactions, are able to perceive the energy of radiation (UV, visible light, and radiation) and convert it into useful reducing power for metabolic processes. They can grow in different culture systems (submerged and solid), and fermentation protocols have been established for large-scale industrial processes. The metal chelation properties of melanin offer interesting possibilities for melanin-based metal ion sensing. Studies in our laboratory showed that melanin extracted from hyperpigment-productive mutant (MEL1) of A. nidulans has the ability to scavenge the biological oxidants, as HOCl, and may be a promising material in cosmetic formulations to protect the skin against possible oxidative damage [31]. WebThe book features nearly all unknown secrets. Bettinger et al. Melanin is a substance in the skin that produces skin pigmentation. 103 pages, Paperback Published September 1, 2001 The Melanin Empath Discover the Knowledge of Melanated Beings Born With Empath Energy Author: Jade Asikiwe Publisher: ISBN: Category: Body, Mind & Spirit Page: 278 View: 702 DOWNLOAD NOW 2020-10-27 in Cindy Sewell The Melanin Empath Survival and Healing Guide to Discover Melanated Beings and Avoid Damage from Negative Energy Author: Cindy Sewell Melanin has also been used to treat various types of malignant cancer tumors, disorders of the immune system including AIDS, diseases of blood origin and disorders due to the disturbances in cell homeostasis, and complex and hardly curable mental disorders (schizophrenia, epilepsy) involving nervous and other regulatory systems. Since melanin has characteristics of functional materials and bioorganic, a growing number of researchers see this pigment with great interest, taking advantage of their properties for numerous biotechnological applications in cosmetics, pharmaceutical, electronic, and food processing industries [12, 19, 35]. 4 (April 2009): 2009 Apr; 10(4): 1419-1429,https://doi.org/10.3390/ijms10041419. Gerald H. Pollack, Xavier Figueroa, and Qing Zhao, Molecules, Water, andRadiant Energy: New Clues for the Origin of Life,International Journal ofMolecular Sciences10, no. Fungal melanins are negatively charged, hydrophobic pigments of high molecular weight formed by oxidative polymerization from phenolic and/or indolic compounds, such as glutaminyl-3,4-dihydroxybenzene (GDHB) or catechol or 1,8-dihydroxynaphthalene (DHN) or 3,4-dihydroxyphenylalanine (DOPA). Others studies suggest that melanin contributes to fungal pathogenesis because this pigment alters the host defense response mechanisms, decreases phagocytosis, and reduces the toxicity of microbicidal peptides, reactive oxygen species, and antifungal drugs as well as to play a significant role in fungal cell wall mechanical strength [27, 28]. The development of these higher cognitive processes allowed for the materialization of sophisticated technologies, the agrarian revolution, hierarchical social structure, and advanced human civilizations. The incorporation of the melanin in solid plastic films of polyvinyl alcohol (PVA-melanin film system) to be used in conjunction with other plastics to make laminated sheets or lenses, including sunglasses, ski goggles, ophthalmic prescription lenses, helmets, windows, light filters for artificial lighting, and other light filters that protect people from potentially damaging UV and high-energy visible light has also been reported [141]. WebMelanin: The Chemical Keys to Black Greatness (Vol. Addeddate 2018-06-15 13:47:24 Identifier MelaninWhatMakesBlackPeopleBlackByLlailaAfrikaPDF Identifier-ark ark:/13960/t6zw89t9z Ocr ABBYY FineReader 11.0 (Extended OCR) Studies have shown that one of the major causes of aging is the surplus free radicals produced during the oxidative metabolism in the human body [108]. Write a reviewor get your copy ofREGENERATE here. Book details & editions. WebLiving Color is the first book to investigate the social history of skin color from prehistory to the present, showing how our body's most visible trait influences our social interactions in profound and complex ways. 50% Discount on the Remaining Status Law Classes NOT on Patreon! However, M. purpureus was not able to grow in media containing peptone, and a maximum yield of the pigment was achieved when the media were supplemented with yeast extract (1%) and monosodium glutamate (5%) as nitrogen source [41]. 2017 The Author(s). 1: the Great Oracle of Tehuti and the Egyptian System of Spiritual Cultivation by Ra Un Nefer Amen WebTHE GREAT BOOK OF MELANIN RESEARCH!!! Search the history of over 797 billion Taken alongside evidence that bacteria that produce pyomelanin, a cousin to melanin, thrive in soil contaminated with uranium,26and the findings that exposure to ionizing radiation actually promotes the growth of certain melanized fungal species inhabiting nuclear reactors, space stations, and the Antarctic mountains, it seems plausible that melanin allows certain organisms to eat radiation.27A study published inPLOSONErevealed that melanin-containing fungal cells saw increased growth relative to nonmelanized cells after exposure to ionizing radiation and that the irradiated melanin from these fungi also changed its electronic properties, which the study noted raised intriguing questions about a potential role for melanin in energy capture and utilization.28. Melanin, the What, the Why and the How: An Introductory Review for Materials Scientists Interested in Flexible and Versatile Polymers. Very likely, melanin photoprotection is also due to its ability to quench excited states of certain molecules and scavenge ROS that may be generated in pigmented cells [126]. Access to Any Private Q&A Livestream With Me! London, SW7 2QJ, You can download the paper by clicking the button above. It was also observed that the pigments vary in the strength of the stable free radical signal detectable by EPR [13, 83]. By Barbara Pilawa, Magdalena Zdybel and Ewa Chodurek. As PhD students, we found it difficult to access the research we needed, so we decided to create a new Open Access publisher that levels the playing field for scientists across the world. In order to compensate for the decreased availability of sunlight, the human body rapidly adjusted, potentially removing the natural sunscreen, melanin, from the skin since it interferes with the production ofvitamin D, a hormone that participates in governing the expression of more than 2,000 genes. These results showed that melanin thin films have great potential in the reconstruction of tissues, being biodegradable, and possess inflammatory response comparable to silicone. In addition, this pigment has a considerable interest biotechnological because it can be produced on a large scale with low cost, making its use for future practical applications economically advantageous. Apart from this scavenging ability, melanin exhibits other biological activities, including thermoregulatory, photoprotective, antimicrobial, antiviral, cytotoxic, anti-inflammatory, radioprotective, and immunomodulatory [13, 17, 18, 3134]. From trees to flowers to food to energy you will find this one extremely rare. I) by Carol Barnes Melanin: The Organizing Molecule Berkley CA: Institute for the Study of Consciousnesses (Thesis) Message To The Blackman in America by Elijah Muhammad Metu Neter Vol. Polymerization of exogenous substrates in this fungus occurs under the action of laccase [19]. Other groups have published various device architectures with applications such as memory (metal-insulator-semiconductor geometries) [131], batteries [132], and biomimetic interfaces [133]. WebLiving Color is the first book to investigate the social history of skin color from prehistory to the present, showing how our body's most visible trait influences our social interactions in profound and complex ways. The pigment production from microorganisms is considered more advantageous because it is a more efficient and cost-effective process than chemical synthesis of pigments. Therefore it is logical to ask whether the consumption of melanin from fungi might protect those higher on the food chainlike humansfrom radiation exposure. In other words, the energy freed up by using melanin in this novel way may have enabled the expansion of energetically intensive brain tissues such as the cerebral cortex, which is responsible for the higher thought processes of speech, information processing, impulse control, and decision making.23. The melanin pigment is not essential for fungal development, but it has been reported to act as fungal armor due to its ability to protect the microorganisms from harmful environmental conditions. Hermit93 WebGREAT BOOK OF MELANIN RESEARCH PUBLIC OFFICIAL BONDS BOOK (POB) Public Official Bonds - Make Them Pay!!! First published October 15, 2009. Print length 103 pages Language English Publisher Lushena Books Publication date 9 (November 2012): 570-76,https://doi.org/10.1089/cbr.2012.1318. Carbon and nitrogen are necessary for cellular metabolism, and these sources are related to the formation of biomass, the type produced pigment, and the yield of the desired substance. Studies have shown that it is possible to use melanin as an ultraviolet, visible and near-infrared absorbing pigment in opthalmic devices, protective eyewear, windows, packaging material, umbrellas, canopies, and other similar media suitable for providing protection from radiation [139, 140]. 38 ] # 1.. What is Status? one extremely rare substance in the skin that skin... Ultrafastnonradiative Relaxation in Electronically Excited eumelanin Constituents, Biophysics Journal95, no the food of the researchers the! In different culture systems ( submerged and solid ), and fermentation have! Pigments in all fungi adjustment may have gained vitamin D accessibility at expense...: //doi.org/10.1016/j.taap.2012.08.002 established for large-scale industrial processes to energy you will find this one extremely rare produces! Be University ) Abstract melanin is a substance in the skin that skin. # 1.. What is Status? [ 101 ] gland is the first gland developed in body... 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